2021 Conference USA Leaders Rushing Defense - When Winning By 8-14 Pts through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Florida International | 2 | 10 | 26 | 2.60 | 0 | 11 | 1 | 1 | 0 |
| 2 | Florida Atlantic | 6 | 30 | 76 | 2.53 | 1 | 31 | 5 | 2 | 1 |
| 3 | Western Kentucky | 8 | 41 | 93 | 2.27 | 0 | 39 | 7 | 7 | 1 |
| 4 | Rice | 5 | 33 | 119 | 3.61 | 2 | 36 | 9 | 8 | 2 |
| 5 | Charlotte | 4 | 28 | 126 | 4.50 | 0 | 15 | 5 | 6 | 0 |
| 6 | Middle Tennessee | 6 | 53 | 164 | 3.09 | 1 | 23 | 13 | 8 | 2 |
| 7 | UTSA | 10 | 58 | 181 | 3.12 | 0 | 32 | 11 | 4 | 1 |
| 8 | Old Dominion | 4 | 45 | 190 | 4.22 | 1 | 55 | 8 | 4 | 2 |
| 9 | UTEP | 7 | 76 | 196 | 2.58 | 2 | 16 | 15 | 6 | 0 |
| 10 | North Texas | 6 | 53 | 270 | 5.09 | 3 | 69 | 14 | 7 | 2 |
| 11 | Marshall | 9 | 65 | 278 | 4.28 | 0 | 31 | 21 | 12 | 3 |
| 12 | UAB | 9 | 65 | 290 | 4.46 | 3 | 35 | 15 | 9 | 3 |
| 13 | Southern Mississippi | 4 | 61 | 294 | 4.82 | 2 | 23 | 16 | 10 | 2 |
| 14 | Louisiana Tech | 6 | 47 | 308 | 6.55 | 5 | 70 | 16 | 12 | 3 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||