2021 Conference USA Leaders Rushing Defense - From Opponent's 1 To 20 Yard Line through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | UAB | 12 | 38 | 83 | 2.18 | 0 | 19 | 2 | 1 | 0 |
| 2 | Old Dominion | 12 | 51 | 147 | 2.88 | 0 | 23 | 5 | 3 | 1 |
| 3 | UTEP | 11 | 41 | 156 | 3.80 | 0 | 38 | 6 | 5 | 1 |
| 4 | Western Kentucky | 13 | 38 | 163 | 4.29 | 0 | 31 | 5 | 4 | 1 |
| 5 | Louisiana Tech | 12 | 52 | 193 | 3.71 | 0 | 30 | 10 | 9 | 2 |
| 6 | UTSA | 14 | 52 | 196 | 3.77 | 0 | 27 | 9 | 8 | 1 |
| 7 | Middle Tennessee | 13 | 51 | 203 | 3.98 | 0 | 17 | 13 | 10 | 0 |
| 8 | Southern Mississippi | 12 | 55 | 209 | 3.80 | 0 | 45 | 5 | 4 | 1 |
| 9 | Charlotte | 12 | 43 | 292 | 6.79 | 1 | 80 | 11 | 7 | 2 |
| 10 | Rice | 10 | 38 | 304 | 8.00 | 0 | 81 | 7 | 6 | 4 |
| 11 | Florida Atlantic | 12 | 59 | 339 | 5.75 | 1 | 94 | 7 | 7 | 4 |
| 12 | Marshall | 12 | 63 | 354 | 5.62 | 1 | 88 | 13 | 10 | 2 |
| 13 | North Texas | 12 | 57 | 369 | 6.47 | 1 | 85 | 9 | 10 | 5 |
| 14 | Florida International | 12 | 72 | 459 | 6.38 | 0 | 56 | 17 | 11 | 4 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||