2021 Conference USA Leaders Tackles - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Solo | Assisted | Total | Total/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Antwon Kincade | Western Ky | SR | DB | 2 | 12 | 12 | 24 | 12.00 |
| 2 | DQ Thomas | MTSU | SR | LB | 1 | 10 | 1 | 11 | 11.00 |
| 2 | KD Davis | N Texas | JR | LB | 1 | 10 | 1 | 11 | 11.00 |
| 2 | Jordan Helm | FAU | SR | S | 1 | 7 | 4 | 11 | 11.00 |
| 5 | Malik Shorts | USM | SO | DB | 1 | 6 | 4 | 10 | 10.00 |
| 5 | Caliph Brice | FAU | SR | ILB | 1 | 3 | 7 | 10 | 10.00 |
| 5 | Teja Young | FAU | SO | S | 1 | 3 | 7 | 10 | 10.00 |
| 8 | DeAngelo Malone | Western Ky | SR | DE | 2 | 6 | 12 | 18 | 9.00 |
| 8 | Tre Hawkins III | ODU | JR | CB | 1 | 8 | 1 | 9 | 9.00 |
| 8 | Jay Stanley | USM | SO | DB | 1 | 7 | 2 | 9 | 9.00 |
| 8 | Trevor Harmanson | UTSA | SR | ILB | 1 | 7 | 2 | 9 | 9.00 |
| 8 | Korel Smith | FAU | SR | CB | 1 | 6 | 3 | 9 | 9.00 |
| 8 | Tariq Woolen | UTSA | SR | CB | 1 | 6 | 3 | 9 | 9.00 |
| 8 | Jordan Young | ODU | SR | LB | 1 | 4 | 5 | 9 | 9.00 |
| 15 | Trey Baldwin | La Tech | SR | LB | 2 | 6 | 11 | 17 | 8.50 |
| 15 | Antonio Montero | Rice | JR | LB | 2 | 5 | 12 | 17 | 8.50 |
| 17 | Jon Alexander | Charlotte | SR | DB | 2 | 11 | 5 | 16 | 8.00 |
| 17 | Reed Blankenship | MTSU | SR | S | 1 | 6 | 2 | 8 | 8.00 |
| 17 | Daniel Jackson | FIU | SR | LB | 1 | 4 | 4 | 8 | 8.00 |
| 20 | Luke Martin | Charlotte | SR | LB | 2 | 8 | 7 | 15 | 7.50 |
| 20 | Naeem Smith | Rice | SR | S | 2 | 7 | 8 | 15 | 7.50 |
| 22 | Pierce Withers | FIU | JR | DB | 1 | 7 | 0 | 7 | 7.00 |
| 22 | Roderick Brown | N Texas | FR | DT | 1 | 7 | 0 | 7 | 7.00 |
| 22 | Chris Jones | FAU | FR | OLB | 1 | 5 | 2 | 7 | 7.00 |
| 22 | Teldrick Ross | MTSU | SO | S | 1 | 5 | 2 | 7 | 7.00 |
| 22 | Tyreke Davis | N Texas | SR | LB | 1 | 5 | 2 | 7 | 7.00 |
| 22 | Zyon Gilbert | FAU | SR | CB | 1 | 4 | 3 | 7 | 7.00 |
| 22 | Noah Wilder | UAB | SR | LB | 1 | 2 | 5 | 7 | 7.00 |
| 22 | Antonio Moultrie | UAB | JR | DL | 1 | 2 | 5 | 7 | 7.00 |
| 30 | Markees Watts | Charlotte | SR | DE | 2 | 9 | 4 | 13 | 6.50 |
| 30 | Will Ignont | Western Ky | JR | LB | 2 | 9 | 4 | 13 | 6.50 |
| 30 | Baylen Buchanan | La Tech | SR | DB | 2 | 7 | 6 | 13 | 6.50 |
| 30 | Kahlef Hailassie | Western Ky | SO | DB | 2 | 6 | 7 | 13 | 6.50 |
| 30 | Elijah Garcia | Rice | SR | DL | 2 | 4 | 9 | 13 | 6.50 |
| 35 | Tyler Murray | Charlotte | SR | LB | 2 | 6 | 6 | 12 | 6.00 |
| 35 | BeeJay Williamson | La Tech | SO | DB | 2 | 4 | 8 | 12 | 6.00 |
| 35 | Dadrian Taylor | UTSA | SR | OLB | 1 | 5 | 1 | 6 | 6.00 |
| 35 | Larry Nixon III | N Texas | SO | LB | 1 | 4 | 2 | 6 | 6.00 |
| 35 | Akileis Leroy | FAU | SR | ILB | 1 | 3 | 3 | 6 | 6.00 |
| 35 | Santrell Latham | USM | JR | LB | 1 | 2 | 4 | 6 | 6.00 |
| 35 | Deshaun Oliver Jr. | UAB | JR | LB | 1 | 0 | 6 | 6 | 6.00 |
| 35 | Antarrius Moultrie | FAU | FR | ILB | 1 | 0 | 6 | 6 | 6.00 |
| 43 | Geo Howard | Charlotte | SR | CB | 2 | 11 | 0 | 11 | 5.50 |
| 43 | Tyler Grubbs | La Tech | FR | LB | 2 | 5 | 6 | 11 | 5.50 |
| 43 | Demetrius Cain | Western Ky | SR | LB | 2 | 4 | 7 | 11 | 5.50 |
| 46 | Jaiden Cole | La Tech | JR | DB | 2 | 3 | 7 | 10 | 5.00 |
| 46 | Richard Dames | FIU | SR | DB | 1 | 5 | 0 | 5 | 5.00 |
| 46 | Makyle Sanders | N Texas | SR | DB | 1 | 5 | 0 | 5 | 5.00 |
| 46 | Gregory Grate | MTSU | JR | S | 1 | 4 | 1 | 5 | 5.00 |
| 46 | Clifford Chattman | UTSA | SR | S | 1 | 4 | 1 | 5 | 5.00 |
Note: To qualify, player must have played in 75% of his team's games.