2022 Conference USA Leaders Tackles - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Solo | Assisted | Total | Total/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jaylen Key | UAB | JR | S | 1 | 9 | 3 | 12 | 12.00 |
| 2 | Tyler Grubbs | La Tech | SO | LB | 2 | 16 | 5 | 21 | 10.50 |
| 3 | Eddie Williams | FAU | JR | ILB | 1 | 9 | 1 | 10 | 10.00 |
| 3 | Justin Prince | UTEP | SR | DB | 1 | 7 | 3 | 10 | 10.00 |
| 5 | Derrick Smith | Western Ky | SR | LB | 2 | 14 | 5 | 19 | 9.50 |
| 6 | BeeJay Williamson | La Tech | JR | DB | 2 | 16 | 2 | 18 | 9.00 |
| 6 | Tyrice Knight | UTEP | JR | LB | 1 | 6 | 3 | 9 | 9.00 |
| 8 | Wayne Jones | Charlotte | JR | DB | 2 | 10 | 6 | 16 | 8.00 |
| 8 | Decorian Patterson | MTSU | JR | CB | 1 | 8 | 0 | 8 | 8.00 |
| 8 | Teldrick Ross | MTSU | JR | S | 1 | 7 | 1 | 8 | 8.00 |
| 8 | Raquon Hartley | MTSU | SO | LB | 1 | 4 | 4 | 8 | 8.00 |
| 8 | Kobe Hylton | UTEP | SO | S | 1 | 3 | 5 | 8 | 8.00 |
| 13 | Kahlef Hailassie | Western Ky | JR | DB | 2 | 10 | 3 | 13 | 6.50 |
| 14 | Kaleb Oliver | Western Ky | SR | DB | 2 | 9 | 3 | 12 | 6.00 |
| 14 | Jalen Jackson | MTSU | SO | CB | 1 | 4 | 2 | 6 | 6.00 |
| 14 | Clifford Chattman | UTSA | SR | S | 1 | 4 | 2 | 6 | 6.00 |
| 14 | Grayson Cash | UAB | SR | S | 1 | 3 | 3 | 6 | 6.00 |
| 14 | Keondre Swoopes | UAB | JR | S | 1 | 3 | 3 | 6 | 6.00 |
| 14 | Damien Miller | UAB | JR | S | 1 | 3 | 3 | 6 | 6.00 |
| 14 | Kirk Lockhart | Rice | JR | S | 1 | 3 | 3 | 6 | 6.00 |
| 14 | Devyn Curtis | MTSU | FR | LB | 1 | 2 | 4 | 6 | 6.00 |
| 14 | Noah Wilder | UAB | SR | LB | 1 | 1 | 5 | 6 | 6.00 |
| 23 | Geo Howard | Charlotte | SR | CB | 2 | 8 | 2 | 10 | 5.00 |
| 23 | Hugh Davis | La Tech | JR | LB | 2 | 7 | 3 | 10 | 5.00 |
| 23 | Steven Parker | Charlotte | FR | S | 2 | 5 | 5 | 10 | 5.00 |
| 23 | Chase Monroe | Charlotte | SR | LB | 2 | 5 | 5 | 10 | 5.00 |
| 23 | Marcus Williams | Rice | FR | SAF | 1 | 5 | 0 | 5 | 5.00 |
| 23 | Devodric Bynum | UAB | SR | CB | 1 | 4 | 1 | 5 | 5.00 |
| 23 | Romain Mungin | FAU | JR | CB | 1 | 4 | 1 | 5 | 5.00 |
| 23 | Morven Joseph | FAU | SO | OLB | 1 | 4 | 1 | 5 | 5.00 |
| 23 | Christian Dixon | MTSU | SR | LB | 1 | 4 | 1 | 5 | 5.00 |
| 23 | Nikia Eason Jr. | UAB | JR | OLB | 1 | 3 | 2 | 5 | 5.00 |
| 23 | Cal Wallerstedt | UTEP | JR | LB | 1 | 2 | 3 | 5 | 5.00 |
| 23 | Brandon Matterson | UTSA | SR | DL | 1 | 2 | 3 | 5 | 5.00 |
| 35 | Jaiden Cole | La Tech | SR | DB | 2 | 6 | 3 | 9 | 4.50 |
| 35 | Brodric Martin | Western Ky | SR | DT | 2 | 6 | 3 | 9 | 4.50 |
| 35 | Comanche Francisco | Charlotte | SO | DB | 2 | 5 | 4 | 9 | 4.50 |
| 35 | Will Ignont | Western Ky | SR | LB | 2 | 5 | 4 | 9 | 4.50 |
| 35 | JaQues Evans | Western Ky | SO | LB | 2 | 5 | 4 | 9 | 4.50 |
| 40 | Talique Allen | Western Ky | FR | DB | 2 | 6 | 2 | 8 | 4.00 |
| 40 | Jaleel McRae | FAU | FR | OLB | 1 | 4 | 0 | 4 | 4.00 |
| 40 | Armani-Eli Adams | FAU | JR | S | 1 | 4 | 0 | 4 | 4.00 |
| 40 | Dwight Toombs II | FAU | SO | S | 1 | 4 | 0 | 4 | 4.00 |
| 40 | Quindarius Dunnigan | MTSU | SO | DE | 1 | 4 | 0 | 4 | 4.00 |
| 40 | George Nyakwol | Rice | SR | SAF | 1 | 4 | 0 | 4 | 4.00 |
| 40 | Gabriel Taylor | Rice | SO | SAF | 1 | 4 | 0 | 4 | 4.00 |
| 40 | Corey Mayfield Jr. | UTSA | SR | CB | 1 | 4 | 0 | 4 | 4.00 |
| 40 | Marlon Bradley | FAU | SO | DE | 1 | 3 | 1 | 4 | 4.00 |
| 40 | Sean Fresch | Rice | SO | CB | 1 | 3 | 1 | 4 | 4.00 |
| 40 | Jadrian Taylor | UTEP | SR | DE | 1 | 3 | 1 | 4 | 4.00 |
Note: To qualify, player must have played in 75% of his team's games.