2021 Conference USA Leaders All Purpose - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Jerreth Sterns | Western Ky | JR | WR | 1 | 0 | 186 | 2 | 0 | 18 | 188 | 10.4 | 188.0 |
| 2 | Rasheen Ali | Marshall | FR | RB | 1 | 160 | 5 | 0 | 0 | 21 | 165 | 7.9 | 165.0 |
| 3 | Mitchell Tinsley | Western Ky | JR | WR | 1 | 0 | 127 | 0 | 0 | 7 | 127 | 18.1 | 127.0 |
| 4 | DeWayne McBride | UAB | SO | RB | 2 | 244 | 0 | 0 | 0 | 41 | 244 | 6.0 | 122.0 |
| 5 | Bub Means | La Tech | FR | WR | 1 | 0 | 95 | 0 | 21 | 7 | 116 | 16.6 | 116.0 |
| 6 | Zakhari Franklin | UTSA | JR | WR | 1 | 0 | 89 | 0 | 0 | 8 | 89 | 11.1 | 89.0 |
| 7 | Brenden Brady | UTSA | SR | RB | 1 | 76 | 8 | 0 | 0 | 17 | 84 | 4.9 | 84.0 |
| 8 | Stone Smartt | ODU | SR | QB | 1 | 1 | 26 | 0 | 52 | 7 | 79 | 11.3 | 79.0 |
| 9 | De'Corian Clark | UTSA | JR | WR | 1 | 2 | 72 | 0 | 0 | 7 | 74 | 10.6 | 74.0 |
| 10 | Elijah Davis | ODU | SO | RB | 1 | 69 | 3 | 0 | 0 | 13 | 72 | 5.5 | 72.0 |
| 11 | Austin Kendall | La Tech | SR | QB | 1 | 71 | 0 | 0 | 0 | 15 | 71 | 4.7 | 71.0 |
| 12 | Malachi Corley | Western Ky | FR | WR | 1 | 0 | 69 | 0 | 0 | 7 | 69 | 9.9 | 69.0 |
| 13 | Grayson Gunter | USM | SR | TE | 1 | 0 | 61 | 0 | 0 | 3 | 61 | 20.3 | 61.0 |
| 14 | Khalan Griffin | Rice | FR | RB | 2 | 121 | 0 | 0 | 0 | 32 | 121 | 3.8 | 60.5 |
| 15 | Marcus Williams Jr. | La Tech | SR | RB | 1 | 59 | -1 | 0 | 0 | 17 | 58 | 3.4 | 58.0 |
| 16 | Willie Johnson | Marshall | SR | WR | 1 | 21 | 0 | 36 | 0 | 5 | 57 | 11.4 | 57.0 |
| 17 | Blake Watson | ODU | SO | RB | 1 | 55 | 1 | 0 | 0 | 16 | 56 | 3.5 | 56.0 |
| 18 | Jermaine Brown Jr. | UAB | JR | RB | 2 | 76 | 19 | 0 | 15 | 19 | 110 | 5.8 | 55.0 |
| 19 | Tre Harris | La Tech | FR | WR | 1 | 0 | 52 | 0 | 0 | 3 | 52 | 17.3 | 52.0 |
| 20 | Smoke Harris | La Tech | SO | WR | 1 | 0 | 39 | 11 | 0 | 8 | 50 | 6.3 | 50.0 |
| 20 | Corey Gammage | Marshall | SO | WR | 1 | 0 | 50 | 0 | 0 | 9 | 50 | 5.6 | 50.0 |
| 22 | Shadeed Ahmed | Marshall | SO | WR | 1 | 0 | 27 | 0 | 22 | 3 | 49 | 16.3 | 49.0 |
| 23 | Jacob Adams | La Tech | JR | FB | 1 | 0 | 48 | 0 | 0 | 3 | 48 | 16.0 | 48.0 |
| 23 | Adam Cofield | Western Ky | SR | RB | 1 | 15 | 33 | 0 | 0 | 9 | 48 | 5.3 | 48.0 |
| 25 | Craig Burt, Jr. | Western Ky | JR | WR | 1 | 0 | 46 | 0 | 0 | 4 | 46 | 11.5 | 46.0 |
| 26 | Jordan Myers | Rice | SR | TE | 2 | 23 | 52 | 0 | 16 | 18 | 91 | 5.1 | 45.5 |
| 27 | Griffin Hebert | La Tech | JR | WR | 1 | 0 | 45 | 0 | 0 | 2 | 45 | 22.5 | 45.0 |
| 28 | Noah Whittington | Western Ky | FR | RB | 1 | 37 | 6 | 0 | 0 | 8 | 43 | 5.4 | 43.0 |
| 29 | Chandler Pittman | USM | FR | RB | 1 | 28 | 14 | 0 | 0 | 7 | 42 | 6.0 | 42.0 |
| 30 | Tykee Ogle-Kellogg | UTSA | JR | WR | 1 | 0 | 41 | 0 | 0 | 2 | 41 | 20.5 | 41.0 |
| 30 | Roger Cray | ODU | SR | CB | 1 | 0 | 0 | 41 | 0 | 3 | 41 | 13.7 | 41.0 |
| 30 | Ty Keyes | USM | FR | QB | 1 | 41 | 0 | 0 | 0 | 12 | 41 | 3.4 | 41.0 |
| 33 | Camron Harrell | USM | JR | DB | 1 | 0 | 0 | 0 | 37 | 2 | 37 | 18.5 | 37.0 |
| 34 | Oscar Cardenas | UTSA | SO | TE | 1 | 0 | 33 | 0 | 0 | 2 | 33 | 16.5 | 33.0 |
| 35 | Ryan Davis | UAB | SO | WR | 2 | 0 | 64 | 0 | 0 | 5 | 64 | 12.8 | 32.0 |
| 36 | Jake Bailey | Rice | SO | WR | 2 | 0 | 62 | 0 | 0 | 5 | 62 | 12.4 | 31.0 |
| 37 | Keondre Swoopes | UAB | JR | S | 2 | 0 | 0 | 0 | 0 | 1 | 61 | 61.0 | 30.5 |
| 38 | Ari Broussard | Rice | SO | RB | 2 | 56 | 0 | 0 | 0 | 14 | 56 | 4.0 | 28.0 |
| 39 | Sean Fresch | Rice | FR | CB | 2 | 0 | 0 | 16 | 39 | 4 | 55 | 13.8 | 27.5 |
| 40 | Samuel Emilus | La Tech | SR | WR | 1 | 0 | 27 | 0 | 0 | 3 | 27 | 9.0 | 27.0 |
| 41 | Joshua Cephus | UTSA | JR | WR | 1 | 0 | 26 | 0 | 0 | 2 | 26 | 13.0 | 26.0 |
| 41 | Jayden Harrison | Marshall | SO | WR | 1 | 0 | 6 | 0 | 20 | 2 | 26 | 13.0 | 26.0 |
| 41 | Dajon Richard | USM | FR | RB | 1 | 7 | 19 | 0 | 0 | 5 | 26 | 5.2 | 26.0 |
| 44 | Jordan Bly | ODU | FR | WR | 1 | 0 | 25 | 0 | 0 | 3 | 25 | 8.3 | 25.0 |
| 45 | Isaiah Graham | La Tech | SR | WR | 1 | 0 | 24 | 0 | 0 | 1 | 24 | 24.0 | 24.0 |
| 45 | Tejhaun Palmer | UAB | JR | WR | 2 | 0 | 48 | 0 | 0 | 3 | 48 | 16.0 | 24.0 |
| 45 | B.J. Daniels | UTSA | SR | RB | 1 | 38 | -14 | 0 | 0 | 4 | 24 | 6.0 | 24.0 |
| 48 | Gerrit Prince | UAB | SR | TE | 2 | 0 | 47 | 0 | 0 | 5 | 47 | 9.4 | 23.5 |
| 49 | Antavious Willis | USM | FR | DB | 1 | 0 | 0 | 0 | 22 | 1 | 22 | 22.0 | 22.0 |
| 50 | Da'quan Bailey-Brown | USM | JR | WR | 1 | 0 | 3 | 18 | 0 | 3 | 21 | 7.0 | 21.0 |
Note: To qualify, player must have played in 75% of his team's games.