2020 Conference USA Leaders Total Defense - Games vs. FBS non-Power 5 Conference Teams Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Florida International | 4 | 893 | 777 | 286 | 1670 | 5.84 | 417.5 |
| 2 | Rice | 5 | 704 | 1004 | 300 | 1708 | 5.69 | 341.6 |
| 3 | UTEP | 5 | 719 | 1104 | 323 | 1823 | 5.64 | 364.6 |
| 4 | Charlotte | 5 | 1010 | 1106 | 333 | 2116 | 6.35 | 423.2 |
| 5 | UAB | 7 | 804 | 1208 | 451 | 2012 | 4.46 | 287.4 |
| 6 | Florida Atlantic | 9 | 1391 | 1689 | 601 | 3080 | 5.12 | 342.2 |
| 7 | Western Kentucky | 10 | 1776 | 1695 | 691 | 3471 | 5.02 | 347.1 |
| 8 | Louisiana Tech | 8 | 1555 | 1723 | 564 | 3278 | 5.81 | 409.8 |
| 9 | Marshall | 9 | 869 | 1759 | 588 | 2628 | 4.47 | 292.0 |
| 10 | Middle Tennessee | 9 | 1997 | 2017 | 663 | 4014 | 6.05 | 446.0 |
| 11 | North Texas | 9 | 2603 | 2049 | 666 | 4652 | 6.98 | 516.9 |
| 12 | Southern Mississippi | 9 | 1786 | 2056 | 645 | 3842 | 5.96 | 426.9 |
| 13 | UTSA | 11 | 1886 | 2370 | 757 | 4256 | 5.62 | 386.9 |