2019 Conference USA Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/13/2020
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Old Dominion | 4 | 376 | 848 | 236 | 1224 | 5.19 | 306.0 |
| 2 | UTSA | 4 | 1003 | 615 | 240 | 1618 | 6.74 | 404.5 |
| 3 | Rice | 4 | 727 | 1006 | 259 | 1733 | 6.69 | 433.3 |
| 4 | North Texas | 4 | 778 | 818 | 264 | 1596 | 6.05 | 399.0 |
| 4 | UTEP | 4 | 708 | 973 | 264 | 1681 | 6.37 | 420.3 |
| 6 | Western Kentucky | 5 | 730 | 964 | 294 | 1694 | 5.76 | 338.8 |
| 7 | Charlotte | 5 | 1010 | 677 | 301 | 1687 | 5.60 | 337.4 |
| 8 | Middle Tennessee | 4 | 1017 | 1009 | 305 | 2026 | 6.64 | 506.5 |
| 9 | Southern Mississippi | 5 | 654 | 1382 | 314 | 2036 | 6.48 | 407.2 |
| 10 | UAB | 5 | 668 | 880 | 315 | 1548 | 4.91 | 309.6 |
| 11 | Florida International | 5 | 830 | 1138 | 338 | 1968 | 5.82 | 393.6 |
| 12 | Marshall | 5 | 974 | 1270 | 360 | 2244 | 6.23 | 448.8 |
| 13 | Florida Atlantic | 5 | 830 | 1320 | 363 | 2150 | 5.92 | 430.0 |
| 14 | Louisiana Tech | 5 | 688 | 1085 | 395 | 1773 | 4.49 | 354.6 |