2018 American Athletic Conference Leaders Total Offense - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 2 | 470 | 716 | 172 | 1186 | 6.90 | 593.0 |
| 2 | South Florida | 2 | 434 | 618 | 158 | 1052 | 6.66 | 526.0 |
| 3 | UCF | 2 | 370 | 448 | 140 | 818 | 5.84 | 409.0 |
| 4 | Connecticut | 1 | 178 | 217 | 68 | 395 | 5.81 | 395.0 |
| 5 | Memphis | 2 | 407 | 379 | 163 | 786 | 4.82 | 393.0 |
| 6 | Temple | 3 | 409 | 753 | 236 | 1162 | 4.92 | 387.3 |
| 7 | Cincinnati | 2 | 450 | 316 | 145 | 766 | 5.28 | 383.0 |
| 8 | Tulane | 2 | 255 | 437 | 137 | 692 | 5.05 | 346.0 |
| 9 | East Carolina | 2 | 251 | 363 | 133 | 614 | 4.62 | 307.0 |
| 10 | Tulsa | 2 | 322 | 291 | 129 | 613 | 4.75 | 306.5 |
| 11 | SMU | 2 | 241 | 320 | 137 | 561 | 4.09 | 280.5 |