2016 American Athletic Conference Leaders Total Offense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 1 | 262 | 250 | 78 | 512 | 6.56 | 512.0 |
| 2 | East Carolina | 3 | 348 | 1059 | 236 | 1407 | 5.96 | 469.0 |
| 3 | South Florida | 3 | 732 | 641 | 199 | 1373 | 6.90 | 457.7 |
| 4 | Memphis | 2 | 324 | 544 | 150 | 868 | 5.79 | 434.0 |
| 5 | UCF | 2 | 470 | 316 | 159 | 786 | 4.94 | 393.0 |
| 6 | Houston | 2 | 153 | 619 | 159 | 772 | 4.86 | 386.0 |
| 7 | SMU | 2 | 252 | 473 | 151 | 725 | 4.80 | 362.5 |
| 8 | Temple | 2 | 18 | 682 | 134 | 700 | 5.22 | 350.0 |
| 9 | Tulane | 1 | 146 | 134 | 70 | 280 | 4.00 | 280.0 |
| 10 | Connecticut | 3 | 261 | 562 | 202 | 823 | 4.07 | 274.3 |
| 11 | Tulsa | 1 | 61 | 127 | 69 | 188 | 2.72 | 188.0 |