2018 Atlantic Coast Conference Leaders Total Defense - Games in August/September Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (Florida) | 5 | 530 | 694 | 309 | 1224 | 3.96 | 244.8 |
| 2 | Clemson | 5 | 475 | 843 | 317 | 1318 | 4.16 | 263.6 |
| 3 | Virginia | 5 | 631 | 992 | 303 | 1623 | 5.36 | 324.6 |
| 4 | North Carolina State | 4 | 417 | 972 | 262 | 1389 | 5.30 | 347.3 |
| 5 | Duke | 5 | 614 | 1132 | 354 | 1746 | 4.93 | 349.2 |
| 6 | Georgia Tech | 5 | 745 | 1035 | 332 | 1780 | 5.36 | 356.0 |
| 7 | Boston College | 5 | 828 | 1087 | 388 | 1915 | 4.94 | 383.0 |
| 8 | Florida State | 5 | 505 | 1422 | 377 | 1927 | 5.11 | 385.4 |
| 9 | Louisville | 5 | 844 | 1085 | 334 | 1929 | 5.78 | 385.8 |
| 10 | North Carolina | 4 | 837 | 708 | 278 | 1545 | 5.56 | 386.3 |
| 11 | Virginia Tech | 4 | 336 | 1216 | 281 | 1552 | 5.52 | 388.0 |
| 12 | Syracuse | 5 | 816 | 1197 | 348 | 2013 | 5.78 | 402.6 |
| 13 | Pittsburgh | 5 | 1004 | 1149 | 342 | 2153 | 6.30 | 430.6 |
| 14 | Wake Forest | 5 | 948 | 1358 | 381 | 2306 | 6.05 | 461.2 |