2018 Atlantic Coast Conference Leaders Rushing Defense - Games vs. Non-Conference Teams Only through 01/07/2019
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Clemson | 6 | 225 | 594 | 2.64 | 1 | 37.50 | 99.00 |
| 2 | Virginia | 5 | 157 | 627 | 3.99 | 6 | 31.40 | 125.40 |
| 2 | North Carolina State | 5 | 151 | 756 | 5.01 | 6 | 30.20 | 151.20 |
| 2 | Florida State | 4 | 141 | 703 | 4.99 | 6 | 35.25 | 175.75 |
| 5 | Duke | 5 | 174 | 586 | 3.37 | 7 | 34.80 | 117.20 |
| 5 | Miami (Florida) | 5 | 205 | 648 | 3.16 | 7 | 41.00 | 129.60 |
| 5 | Boston College | 4 | 152 | 530 | 3.49 | 7 | 38.00 | 132.50 |
| 5 | Pittsburgh | 5 | 178 | 694 | 3.90 | 7 | 35.60 | 138.80 |
| 5 | Syracuse | 5 | 180 | 778 | 4.32 | 7 | 36.00 | 155.60 |
| 5 | North Carolina | 3 | 132 | 513 | 3.89 | 7 | 44.00 | 171.00 |
| 11 | Georgia Tech | 5 | 194 | 904 | 4.66 | 8 | 38.80 | 180.80 |
| 12 | Wake Forest | 5 | 209 | 935 | 4.47 | 9 | 41.80 | 187.00 |
| 13 | Louisville | 4 | 181 | 904 | 4.99 | 10 | 45.25 | 226.00 |
| 14 | Virginia Tech | 5 | 166 | 826 | 4.98 | 13 | 33.20 | 165.20 |