2018 Conference USA Leaders Total Defense - Games vs. FBS (I-A) Teams Only through 01/07/2019
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 10 | 1029 | 1834 | 613 | 2863 | 4.67 | 286.3 |
| 2 | Charlotte | 11 | 1277 | 2484 | 637 | 3761 | 5.90 | 341.9 |
| 3 | UTEP | 11 | 2242 | 2176 | 735 | 4418 | 6.01 | 401.6 |
| 4 | Rice | 12 | 2018 | 3397 | 785 | 5415 | 6.90 | 451.3 |
| 5 | Western Kentucky | 11 | 1932 | 2803 | 792 | 4735 | 5.98 | 430.5 |
| 6 | Florida Atlantic | 11 | 2113 | 2648 | 805 | 4761 | 5.91 | 432.8 |
| 7 | Louisiana Tech | 12 | 1876 | 2275 | 815 | 4151 | 5.09 | 345.9 |
| 7 | UTSA | 12 | 1923 | 3303 | 815 | 5226 | 6.41 | 435.5 |
| 9 | UAB | 13 | 1498 | 2513 | 820 | 4011 | 4.89 | 308.5 |
| 10 | Florida International | 12 | 2327 | 2413 | 822 | 4740 | 5.77 | 395.0 |
| 11 | Old Dominion | 11 | 2525 | 2844 | 838 | 5369 | 6.41 | 488.1 |
| 12 | Marshall | 12 | 1216 | 3000 | 849 | 4216 | 4.97 | 351.3 |
| 13 | North Texas | 12 | 1414 | 3160 | 855 | 4574 | 5.35 | 381.2 |
| 14 | Middle Tennessee | 13 | 2203 | 2627 | 871 | 4830 | 5.55 | 371.5 |