2018 Conference USA Leaders Rushing Defense - Games vs. Non-Conference Teams Only through 01/07/2019
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 3 | 88 | 356 | 4.05 | 1 | 29.33 | 118.67 |
| 2 | Charlotte | 4 | 112 | 292 | 2.61 | 5 | 28.00 | 73.00 |
| 3 | UTSA | 4 | 136 | 547 | 4.02 | 6 | 34.00 | 136.75 |
| 4 | Western Kentucky | 4 | 147 | 700 | 4.76 | 5 | 36.75 | 175.00 |
| 5 | Old Dominion | 4 | 151 | 807 | 5.34 | 8 | 37.75 | 201.75 |
| 6 | North Texas | 5 | 163 | 593 | 3.64 | 8 | 32.60 | 118.60 |
| 7 | Rice | 5 | 169 | 910 | 5.38 | 12 | 33.80 | 182.00 |
| 8 | Florida Atlantic | 4 | 170 | 883 | 5.19 | 12 | 42.50 | 220.75 |
| 9 | UTEP | 4 | 176 | 1021 | 5.80 | 8 | 44.00 | 255.25 |
| 10 | Marshall | 5 | 181 | 585 | 3.23 | 6 | 36.20 | 117.00 |
| 11 | Middle Tennessee | 5 | 186 | 975 | 5.24 | 8 | 37.20 | 195.00 |
| 12 | Louisiana Tech | 5 | 199 | 852 | 4.28 | 11 | 39.80 | 170.40 |
| 12 | Florida International | 5 | 199 | 956 | 4.80 | 4 | 39.80 | 191.20 |
| 12 | UAB | 5 | 199 | 986 | 4.95 | 9 | 39.80 | 197.20 |