2016 Iowa State Cyclones Total Defense Split Stats through 01/09/2017
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 12 | 2618 | 2817 | 911 | 5435 | 5.97 | 452.9 |
| at Home | 7 | 1630 | 1510 | 533 | 3140 | 5.89 | 448.6 |
| on Road/Neutral Site | 5 | 988 | 1307 | 378 | 2295 | 6.07 | 459.0 |
| in Wins | 3 | 505 | 548 | 221 | 1053 | 4.76 | 351.0 |
| in Losses | 9 | 2113 | 2269 | 690 | 4382 | 6.35 | 486.9 |
| vs. Conference | 9 | 2011 | 2290 | 686 | 4301 | 6.27 | 477.9 |
| vs. Non-Conference | 3 | 607 | 527 | 225 | 1134 | 5.04 | 378.0 |
| vs. Ranked (AP) | 4 | 727 | 1257 | 293 | 1984 | 6.77 | 496.0 |
| vs. Unranked (AP) | 8 | 1891 | 1560 | 618 | 3451 | 5.58 | 431.4 |
| vs. FBS (I-A) | 11 | 2386 | 2682 | 826 | 5068 | 6.14 | 460.7 |
| vs. FCS (I-AA) | 1 | 232 | 135 | 85 | 367 | 4.32 | 367.0 |
| vs. FBS Winning | 6 | 1443 | 1586 | 448 | 3029 | 6.76 | 504.8 |
| vs. FBS Non-Winning | 5 | 943 | 1096 | 378 | 2039 | 5.39 | 407.8 |
| vs. FBS Power 5 | 10 | 2209 | 2527 | 752 | 4736 | 6.30 | 473.6 |
| vs. FBS non-Power 5 | 1 | 177 | 155 | 74 | 332 | 4.49 | 332.0 |
| in August/September | 4 | 836 | 779 | 297 | 1615 | 5.44 | 403.8 |
| in October | 4 | 1033 | 976 | 317 | 2009 | 6.34 | 502.3 |
| in November | 4 | 749 | 1062 | 297 | 1811 | 6.10 | 452.8 |
| in December/January | 0 | 0 | 0 | 0 | 0 | - | - |