2016 American Athletic Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulane | 1 | 34 | 79 | 2.32 | 1 | 34.00 | 79.00 |
| 2 | Houston | 2 | 66 | 171 | 2.59 | 1 | 33.00 | 85.50 |
| 3 | Cincinnati | 1 | 25 | 103 | 4.12 | 1 | 25.00 | 103.00 |
| 4 | Connecticut | 3 | 108 | 356 | 3.30 | 3 | 36.00 | 118.67 |
| 5 | Temple | 2 | 80 | 241 | 3.01 | 5 | 40.00 | 120.50 |
| 6 | East Carolina | 3 | 101 | 499 | 4.94 | 8 | 33.67 | 166.33 |
| 7 | UCF | 2 | 91 | 365 | 4.01 | 6 | 45.50 | 182.50 |
| 8 | Memphis | 2 | 75 | 384 | 5.12 | 5 | 37.50 | 192.00 |
| 9 | SMU | 2 | 86 | 412 | 4.79 | 3 | 43.00 | 206.00 |
| 10 | South Florida | 3 | 152 | 768 | 5.05 | 8 | 50.67 | 256.00 |
| 11 | Tulsa | 1 | 48 | 268 | 5.58 | 4 | 48.00 | 268.00 |