2025 American Conference Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 09/01/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulane | 1 | 27 | 76 | 2.81 | 0 | 27.00 | 76.00 |
| 2 | East Carolina | 1 | 36 | 105 | 2.92 | 2 | 36.00 | 105.00 |
| 3 | UTSA | 1 | 23 | 108 | 4.70 | 1 | 23.00 | 108.00 |
| 4 | Florida Atlantic | 1 | 30 | 112 | 3.73 | 0 | 30.00 | 112.00 |