2016 American Athletic Conference Leaders Total Defense - Games vs. Non-Conference Teams Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Houston | 5 | 346 | 829 | 291 | 1175 | 4.04 | 235.0 |
| 2 | UCF | 5 | 559 | 907 | 347 | 1466 | 4.22 | 293.2 |
| 3 | Tulane | 4 | 401 | 798 | 264 | 1199 | 4.54 | 299.8 |
| 4 | Temple | 5 | 850 | 827 | 343 | 1677 | 4.89 | 335.4 |
| 5 | Cincinnati | 4 | 552 | 925 | 283 | 1477 | 5.22 | 369.3 |
| 6 | Connecticut | 4 | 396 | 1100 | 262 | 1496 | 5.71 | 374.0 |
| 7 | Tulsa | 5 | 706 | 1174 | 367 | 1880 | 5.12 | 376.0 |
| 8 | East Carolina | 4 | 647 | 949 | 249 | 1596 | 6.41 | 399.0 |
| 9 | Memphis | 5 | 847 | 1236 | 377 | 2083 | 5.53 | 416.6 |
| 10 | Navy | 5 | 886 | 1226 | 352 | 2112 | 6.00 | 422.4 |
| 11 | SMU | 4 | 592 | 1207 | 332 | 1799 | 5.42 | 449.8 |
| 12 | South Florida | 5 | 1052 | 1235 | 430 | 2287 | 5.32 | 457.4 |