2016 American Athletic Conference Leaders Interceptions - Games in August/September Only through 01/09/2017
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Parry Nickerson | Tulane | JR | CB | 4 | 2 | 133 | 1 | 0.50 |
| 2 | Tyrell Gilbert | Cincinnati | SO | S | 4 | 2 | 84 | 1 | 0.50 |
| 3 | Steven Taylor | Houston | SR | OLB | 5 | 1 | 74 | 1 | 0.20 |
| 4 | Kolton Shindelar | Tulsa | JR | DE | 4 | 1 | 65 | 1 | 0.25 |
| 5 | Jordan Wyatt | SMU | SO | DB | 4 | 3 | 62 | 1 | 0.75 |
| 6 | Jonathan Wilson | Memphis | FR | DL | 3 | 1 | 61 | 1 | 0.33 |
| 7 | Nigel Harris | S Florida | SR | LB | 4 | 1 | 49 | 0 | 0.25 |
| 8 | Delvon Randall | Temple | SO | DB | 4 | 2 | 36 | 0 | 0.50 |
| 9 | Horace Richardson | SMU | SR | DB | 4 | 3 | 31 | 0 | 0.75 |
| 10 | Howard Wilson | Houston | SO | CB | 5 | 3 | 28 | 1 | 0.60 |
| 10 | Genard Avery | Memphis | JR | LB | 3 | 1 | 28 | 1 | 0.33 |
| 12 | Mike Tyson | Cincinnati | SR | S | 4 | 3 | 27 | 0 | 0.75 |
| 13 | Darrion Millines | SMU | SR | DB | 4 | 2 | 26 | 0 | 0.50 |
| 13 | Jahmahl Pardner | Memphis | SR | DB | 3 | 1 | 26 | 0 | 0.33 |
| 15 | Drico Johnson | UCF | SR | DB | 4 | 1 | 25 | 0 | 0.25 |
| 16 | Jesse Brubaker | Tulsa | JR | DT | 4 | 1 | 24 | 1 | 0.25 |
| 17 | Alex Thomas | Cincinnati | SO | CB | 4 | 2 | 22 | 0 | 0.50 |
| 17 | Tajee Fullwood | S Florida | JR | CB | 4 | 1 | 22 | 0 | 0.25 |
| 19 | Rodney Clemons | SMU | FR | DB | 4 | 1 | 21 | 0 | 0.25 |
| 20 | Arthur Maulet | Memphis | SR | DB | 3 | 1 | 18 | 0 | 0.33 |
| 21 | Donnie Lewis Jr. | Tulane | SO | CB | 4 | 1 | 12 | 0 | 0.25 |
| 22 | Grant Coleman | Cincinnati | JR | CB | 4 | 1 | 11 | 0 | 0.25 |
| 23 | Travon Simmons | ECU | JR | DB | 4 | 1 | 7 | 0 | 0.25 |