2016 Atlantic Coast Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 13 | 16 | 255 | 2 | 1.23 |
| 2 | Louisville | 10 | 14 | 228 | 1 | 1.40 |
| 3 | Virginia Tech | 11 | 13 | 49 | 0 | 1.18 |
| 3 | Florida State | 11 | 13 | 37 | 0 | 1.18 |
| 5 | Georgia Tech | 11 | 11 | 137 | 1 | 1.00 |
| 6 | Wake Forest | 9 | 10 | 187 | 2 | 1.11 |
| 7 | Syracuse | 8 | 8 | 58 | 0 | 1.00 |
| 7 | Boston College | 9 | 8 | 131 | 0 | 0.89 |
| 9 | Virginia | 9 | 7 | 65 | 0 | 0.78 |
| 9 | Duke | 9 | 7 | 50 | 1 | 0.78 |
| 9 | Pittsburgh | 11 | 7 | 149 | 2 | 0.64 |
| 12 | North Carolina State | 9 | 6 | 85 | 2 | 0.67 |
| 13 | Miami (Florida) | 9 | 4 | 13 | 0 | 0.44 |