2016 Atlantic Coast Conference Leaders Passes Defended - Games in October Only through 01/09/2017
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Virginia | 4 | 6 | 21 | 27 | 6.75 |
| 2 | Virginia Tech | 4 | 5 | 20 | 25 | 6.25 |
| 3 | Clemson | 4 | 5 | 18 | 23 | 5.75 |
| 4 | Louisville | 4 | 8 | 13 | 21 | 5.25 |
| 5 | North Carolina State | 5 | 3 | 23 | 26 | 5.20 |
| 6 | Florida State | 4 | 5 | 15 | 20 | 5.00 |
| 7 | North Carolina | 4 | 0 | 19 | 19 | 4.75 |
| 8 | Miami (Florida) | 5 | 2 | 20 | 22 | 4.40 |
| 9 | Boston College | 4 | 3 | 13 | 16 | 4.00 |
| 10 | Syracuse | 4 | 4 | 11 | 15 | 3.75 |
| 11 | Pittsburgh | 4 | 2 | 10 | 12 | 3.00 |
| 12 | Wake Forest | 4 | 3 | 8 | 11 | 2.75 |
| 13 | Duke | 4 | 2 | 7 | 9 | 2.25 |
| 14 | Georgia Tech | 4 | 1 | 6 | 7 | 1.75 |