2016 Atlantic Coast Conference Leaders Total Defense - Games vs. FBS (I-A) Teams Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | North Carolina State | 12 | 1350 | 3068 | 847 | 4418 | 5.22 | 368.2 |
| 2 | Boston College | 12 | 1366 | 2611 | 756 | 3977 | 5.26 | 331.4 |
| 3 | Louisville | 13 | 1497 | 2692 | 894 | 4189 | 4.69 | 322.2 |
| 4 | Pittsburgh | 12 | 1502 | 4212 | 920 | 5714 | 6.21 | 476.2 |
| 5 | Florida State | 12 | 1512 | 2732 | 802 | 4244 | 5.29 | 353.7 |
| 6 | Miami (Florida) | 12 | 1689 | 2604 | 876 | 4293 | 4.90 | 357.8 |
| 7 | Wake Forest | 12 | 1795 | 2928 | 861 | 4723 | 5.49 | 393.6 |
| 8 | Virginia Tech | 13 | 1877 | 2733 | 893 | 4610 | 5.16 | 354.6 |
| 9 | Clemson | 14 | 1896 | 2674 | 953 | 4570 | 4.80 | 326.4 |
| 10 | Duke | 11 | 2061 | 2803 | 737 | 4864 | 6.60 | 442.2 |
| 11 | Virginia | 11 | 2093 | 2742 | 770 | 4835 | 6.28 | 439.5 |
| 12 | Georgia Tech | 12 | 2154 | 2747 | 839 | 4901 | 5.84 | 408.4 |
| 13 | North Carolina | 11 | 2402 | 2037 | 821 | 4439 | 5.41 | 403.5 |
| 14 | Syracuse | 11 | 2655 | 3215 | 814 | 5870 | 7.21 | 533.6 |