2016 Big 12 Conference Leaders Passes Defended - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Oklahoma | 11 | 9 | 50 | 59 | 5.36 |
| 2 | TCU | 11 | 6 | 46 | 52 | 4.73 |
| 3 | West Virginia | 11 | 10 | 41 | 51 | 4.64 |
| 3 | Texas Tech | 10 | 3 | 41 | 44 | 4.40 |
| 5 | Kansas State | 11 | 13 | 40 | 53 | 4.82 |
| 6 | Texas | 10 | 10 | 38 | 48 | 4.80 |
| 6 | Iowa State | 10 | 5 | 38 | 43 | 4.30 |
| 8 | Oklahoma State | 11 | 13 | 36 | 49 | 4.45 |
| 9 | Kansas | 9 | 8 | 31 | 39 | 4.33 |
| 10 | Baylor | 9 | 7 | 28 | 35 | 3.89 |