2016 Big 12 Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 01/09/2017
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jordan Evans | Oklahoma | SR | LB | 11 | 4 | 145 | 2 | 0.36 |
| 2 | Ryan Reid | Baylor | SR | CB | 9 | 3 | 116 | 1 | 0.33 |
| 2 | Brandon Stewart | Kansas | SR | CB | 9 | 3 | 71 | 1 | 0.33 |
| 2 | Duke Shelley | Kansas St | SO | DB | 9 | 3 | 29 | 1 | 0.33 |
| 2 | Donnie Starks | Kansas St | SR | DB | 11 | 3 | 64 | 1 | 0.27 |
| 2 | D.J. Reed | Kansas St | SO | DB | 11 | 2 | 35 | 1 | 0.18 |
| 2 | Kamari Cotton-Moya | Iowa State | JR | DB | 9 | 1 | 48 | 1 | 0.11 |
| 2 | Ranthony Texada | TCU | JR | CB | 11 | 1 | 28 | 1 | 0.09 |