2016 Conference USA Leaders Total Defense - Games in November Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 3 | 303 | 470 | 191 | 773 | 4.05 | 257.7 |
| 2 | Old Dominion | 4 | 539 | 722 | 249 | 1261 | 5.06 | 315.3 |
| 3 | Louisiana Tech | 3 | 297 | 728 | 225 | 1025 | 4.56 | 341.7 |
| 4 | Rice | 4 | 930 | 756 | 244 | 1686 | 6.91 | 421.5 |
| 5 | UTEP | 4 | 723 | 766 | 263 | 1489 | 5.66 | 372.3 |
| 6 | Florida International | 3 | 615 | 794 | 213 | 1409 | 6.62 | 469.7 |
| 7 | Southern Mississippi | 4 | 592 | 799 | 234 | 1391 | 5.94 | 347.8 |
| 8 | Middle Tennessee | 4 | 940 | 883 | 341 | 1823 | 5.35 | 455.8 |
| 9 | Marshall | 4 | 813 | 909 | 266 | 1722 | 6.47 | 430.5 |
| 10 | North Texas | 4 | 1022 | 935 | 273 | 1957 | 7.17 | 489.3 |
| 11 | UTSA | 4 | 481 | 1029 | 256 | 1510 | 5.90 | 377.5 |
| 12 | Florida Atlantic | 4 | 1098 | 1077 | 289 | 2175 | 7.53 | 543.8 |
| 13 | Charlotte | 4 | 562 | 1360 | 335 | 1922 | 5.74 | 480.5 |