2016 Conference USA Leaders Total Defense - All Games through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Southern Mississippi | 13 | 1949 | 2274 | 739 | 4223 | 5.71 | 324.8 |
| 2 | UTEP | 12 | 2524 | 2508 | 822 | 5032 | 6.12 | 419.3 |
| 3 | North Texas | 13 | 3114 | 2603 | 942 | 5717 | 6.07 | 439.8 |
| 4 | Florida International | 12 | 2385 | 2830 | 823 | 5215 | 6.34 | 434.6 |
| 5 | Old Dominion | 13 | 2043 | 2944 | 921 | 4987 | 5.41 | 383.6 |
| 6 | UTSA | 13 | 2112 | 2984 | 895 | 5096 | 5.69 | 392.0 |
| 7 | Marshall | 12 | 2421 | 3044 | 860 | 5465 | 6.35 | 455.4 |
| 8 | Florida Atlantic | 12 | 2945 | 3221 | 892 | 6166 | 6.91 | 513.8 |
| 9 | Middle Tennessee | 13 | 2583 | 3260 | 1068 | 5843 | 5.47 | 449.5 |
| 10 | Rice | 12 | 2602 | 3452 | 815 | 6054 | 7.43 | 504.5 |
| 11 | Charlotte | 12 | 1721 | 3718 | 902 | 5439 | 6.03 | 453.3 |
| 12 | Louisiana Tech | 14 | 2047 | 3846 | 1018 | 5893 | 5.79 | 420.9 |
| 13 | Western Kentucky | 14 | 1361 | 3911 | 1014 | 5272 | 5.20 | 376.6 |