2022 Atlantic Coast Conference Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Pittsburgh | 11 | 42.0 | 282 | 3.82 |
| 2 | Clemson | 11 | 40.0 | 261 | 3.64 |
| 3 | Louisville | 9 | 35.0 | 235 | 3.89 |
| 3 | Florida State | 11 | 35.0 | 224 | 3.18 |
| 5 | Miami (Florida) | 9 | 30.0 | 148 | 3.33 |
| 6 | Syracuse | 10 | 26.0 | 156 | 2.60 |
| 7 | Duke | 10 | 25.0 | 179 | 2.50 |
| 7 | North Carolina State | 10 | 25.0 | 171 | 2.50 |
| 7 | Virginia | 8 | 25.0 | 145 | 3.13 |
| 10 | Georgia Tech | 10 | 22.0 | 131 | 2.20 |
| 10 | Boston College | 9 | 22.0 | 116 | 2.44 |
| 12 | Wake Forest | 10 | 20.0 | 161 | 2.00 |
| 13 | Virginia Tech | 8 | 14.0 | 106 | 1.75 |
| 14 | North Carolina | 10 | 10.0 | 77 | 1.00 |