2022 Atlantic Coast Conference Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Clemson | 4 | 11.0 | 53 | 2.75 |
| 2 | Louisville | 3 | 8.0 | 50 | 2.67 |
| 3 | Syracuse | 4 | 7.0 | 54 | 1.75 |
| 3 | Florida State | 2 | 7.0 | 31 | 3.50 |
| 5 | Miami (Florida) | 3 | 6.0 | 49 | 2.00 |
| 5 | Georgia Tech | 4 | 6.0 | 39 | 1.50 |
| 5 | Pittsburgh | 2 | 6.0 | 29 | 3.00 |
| 8 | North Carolina | 4 | 3.0 | 23 | 0.75 |
| 8 | Wake Forest | 2 | 3.0 | 19 | 1.50 |
| 10 | Boston College | 3 | 2.0 | 7 | 0.67 |
| 11 | Virginia Tech | 1 | 1.0 | 12 | 1.00 |
| 11 | North Carolina State | 2 | 1.0 | 10 | 0.50 |
| 11 | Duke | 1 | 1.0 | 8 | 1.00 |