2018 Atlantic Coast Conference Leaders Sacks - Games vs. FBS Power 5 Conference Teams Only through 01/07/2019
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Clemson | 12 | 40.0 | 252 | 3.33 |
| 2 | Syracuse | 9 | 32.0 | 223 | 3.56 |
| 3 | Miami (Florida) | 10 | 31.0 | 191 | 3.10 |
| 4 | North Carolina | 9 | 27.0 | 164 | 3.00 |
| 4 | North Carolina State | 9 | 27.0 | 162 | 3.00 |
| 6 | Florida State | 9 | 24.0 | 173 | 2.67 |
| 6 | Boston College | 9 | 24.0 | 172 | 2.67 |
| 8 | Pittsburgh | 11 | 23.0 | 158 | 2.09 |
| 9 | Virginia | 10 | 20.0 | 125 | 2.00 |
| 10 | Duke | 10 | 18.0 | 105 | 1.80 |
| 11 | Virginia Tech | 8 | 17.0 | 106 | 2.13 |
| 12 | Wake Forest | 8 | 13.0 | 70 | 1.63 |
| 13 | Georgia Tech | 10 | 12.0 | 74 | 1.20 |
| 14 | Louisville | 10 | 7.0 | 42 | 0.70 |