2021 Big Ten Conference Leaders Total Defense - Games in December/January Only through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Minnesota | 1 | 66 | 140 | 58 | 206 | 3.55 | 206.0 |
| 2 | Wisconsin | 1 | 60 | 159 | 54 | 219 | 4.06 | 219.0 |
| 3 | Maryland | 1 | 122 | 137 | 67 | 259 | 3.87 | 259.0 |
| 4 | Michigan State | 1 | 104 | 170 | 55 | 274 | 4.98 | 274.0 |
| 5 | Michigan | 2 | 294 | 506 | 137 | 800 | 5.84 | 400.0 |
| 6 | Iowa | 2 | 332 | 483 | 137 | 815 | 5.95 | 407.5 |
| 7 | Penn State | 1 | 353 | 98 | 78 | 451 | 5.78 | 451.0 |
| 8 | Rutgers | 1 | 148 | 304 | 76 | 452 | 5.95 | 452.0 |
| 9 | Ohio State | 1 | 226 | 237 | 68 | 463 | 6.81 | 463.0 |
| 10 | Purdue | 1 | 281 | 378 | 105 | 659 | 6.28 | 659.0 |