2025 Mid-American Conference Leaders Opponent First Downs - Games vs. FBS Power 5 Conference Teams Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Eastern Michigan | 1 | 14 | 8 | 3 | 25 | 25.0 |
| 2 | Toledo | 2 | 19 | 10 | 8 | 37 | 18.5 |
| 3 | Buffalo | 1 | 12 | 13 | 2 | 27 | 27.0 |
| 4 | Western Michigan | 2 | 18 | 17 | 5 | 40 | 20.0 |
| 5 | Northern Illinois | 2 | 21 | 19 | 4 | 44 | 22.0 |
| 6 | Akron | 1 | 9 | 22 | 0 | 31 | 31.0 |
| 7 | Bowling Green | 2 | 12 | 23 | 4 | 39 | 19.5 |
| 8 | Central Michigan | 2 | 26 | 26 | 5 | 57 | 28.5 |
| 9 | Massachusetts | 2 | 25 | 28 | 0 | 53 | 26.5 |
| 10 | Ball State | 2 | 19 | 29 | 2 | 50 | 25.0 |
| 10 | Miami (OH) | 2 | 20 | 29 | 5 | 54 | 27.0 |
| 10 | Kent State | 3 | 55 | 29 | 3 | 87 | 29.0 |
| 13 | Ohio | 3 | 27 | 34 | 4 | 65 | 21.7 |