2025 Mid-American Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 11/22/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Michigan | 1 | 30 | 182 | 6.07 | 2 | 30.00 | 182.00 |
| 2 | Ohio | 1 | 31 | 225 | 7.26 | 1 | 31.00 | 225.00 |
| 3 | Central Michigan | 2 | 81 | 505 | 6.23 | 10 | 40.50 | 252.50 |
| 4 | Kent State | 2 | 83 | 415 | 5.00 | 4 | 41.50 | 207.50 |