2025 Big Ten Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 10/04/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Indiana | 1 | 2 | 159 | 45 | 161 | 3.58 | 161.0 |
| 2 | Northwestern | 1 | 176 | 197 | 56 | 373 | 6.66 | 373.0 |
| 2 | Nebraska | 1 | 286 | 105 | 56 | 391 | 6.98 | 391.0 |
| 4 | Minnesota | 1 | 133 | 341 | 58 | 474 | 8.17 | 474.0 |
| 5 | Washington | 1 | 149 | 208 | 62 | 357 | 5.76 | 357.0 |
| 5 | USC | 1 | 171 | 331 | 62 | 502 | 8.10 | 502.0 |
| 7 | Illinois | 1 | 312 | 267 | 72 | 579 | 8.04 | 579.0 |
| 8 | Michigan | 1 | 138 | 270 | 74 | 408 | 5.51 | 408.0 |
| 9 | Penn State | 1 | 176 | 248 | 78 | 424 | 5.44 | 424.0 |
| 10 | Wisconsin | 2 | 247 | 652 | 114 | 899 | 7.89 | 449.5 |
| 11 | Iowa | 2 | 208 | 367 | 119 | 575 | 4.83 | 287.5 |
| 12 | Purdue | 2 | 371 | 671 | 126 | 1042 | 8.27 | 521.0 |