2025 Big Ten Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 09/11/2025
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Peyton Woodyard | Oregon | SO | DB | 1 | 1 | 30 | 1 | 1.00 |
| 1 | Jerry Mixon | Oregon | JR | ILB | 1 | 1 | 26 | 1 | 1.00 |
| 1 | Jermaine Mathews Jr. | Ohio State | JR | CB | 1 | 1 | 5 | 0 | 1.00 |
| 1 | TJ Metcalf | Michigan | JR | DB | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Malcolm Hartzog, Jr. | Nebraska | SR | DB | 1 | 1 | 0 | 0 | 1.00 |
| 1 | Tanner Heckel | Illinois | SO | DB | 1 | 1 | -1 | 0 | 1.00 |