2025 American Conference Leaders Opponent First Downs - Games vs. FBS non-Power 5 Conference Teams Only through 11/01/2025
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | East Carolina | 5 | 36 | 45 | 5 | 86 | 17.2 |
| 2 | Memphis | 7 | 42 | 77 | 13 | 132 | 18.9 |
| 3 | Rice | 7 | 55 | 64 | 17 | 136 | 19.4 |
| 4 | UTSA | 6 | 46 | 59 | 17 | 122 | 20.3 |
| 4 | Army | 6 | 51 | 65 | 6 | 122 | 20.3 |
| 4 | UAB | 6 | 56 | 55 | 11 | 122 | 20.3 |
| 7 | North Texas | 7 | 91 | 46 | 6 | 143 | 20.4 |
| 8 | Temple | 6 | 52 | 58 | 14 | 124 | 20.7 |
| 9 | Florida Atlantic | 6 | 74 | 43 | 13 | 130 | 21.7 |
| 10 | Tulane | 5 | 49 | 49 | 12 | 110 | 22.0 |
| 10 | Navy | 7 | 60 | 84 | 10 | 154 | 22.0 |
| 12 | Tulsa | 6 | 69 | 67 | 8 | 144 | 24.0 |
| 13 | USF | 5 | 38 | 68 | 15 | 121 | 24.2 |
| 14 | Charlotte | 6 | 73 | 76 | 6 | 155 | 25.8 |