2025 Atlantic Coast Conference Leaders Interceptions - Games vs. Ranked Teams Only (AP Poll) through 11/22/2025
| Name | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 2 | 4 | 169 | 2 | 2.00 |
| 2 | Florida State | 3 | 3 | 31 | 0 | 1.00 |
| 3 | Duke | 3 | 2 | 18 | 1 | 0.67 |
| 4 | North Carolina | 1 | 1 | 16 | 0 | 1.00 |
| 5 | SMU | 1 | 2 | 15 | 0 | 2.00 |
| 6 | Miami (FL) | 1 | 1 | 12 | 0 | 1.00 |
| 7 | Louisville | 3 | 5 | 5 | 0 | 1.67 |
| 8 | NC State | 4 | 3 | 0 | 0 | 0.75 |
| 8 | Virginia Tech | 3 | 1 | 0 | 0 | 0.33 |