2025 Atlantic Coast Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 09/12/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Miami (FL) | 1 | 28 | 93 | 3.32 | 1 | 28.00 | 93.00 |
| 2 | Florida State | 1 | 29 | 87 | 3.00 | 0 | 29.00 | 87.00 |
| 3 | Clemson | 1 | 31 | 108 | 3.48 | 1 | 31.00 | 108.00 |
| 4 | Virginia Tech | 1 | 37 | 119 | 3.22 | 1 | 37.00 | 119.00 |
| 5 | Syracuse | 1 | 40 | 246 | 6.15 | 2 | 40.00 | 246.00 |
| 6 | Duke | 1 | 42 | 123 | 2.93 | 3 | 42.00 | 123.00 |