2025 Atlantic Coast Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 10/25/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Virginia | 1 | 27 | 54 | 2.00 | 1 | 27.00 | 54.00 |
| 2 | Louisville | 2 | 56 | 151 | 2.70 | 3 | 28.00 | 75.50 |
| 3 | Miami (FL) | 2 | 59 | 212 | 3.59 | 2 | 29.50 | 106.00 |
| 4 | Boston College | 1 | 31 | 317 | 10.23 | 4 | 31.00 | 317.00 |
| 5 | Pittsburgh | 1 | 34 | 53 | 1.56 | 1 | 34.00 | 53.00 |
| 5 | North Carolina | 1 | 34 | 59 | 1.74 | 1 | 34.00 | 59.00 |
| 7 | NC State | 2 | 71 | 400 | 5.63 | 5 | 35.50 | 200.00 |
| 8 | Duke | 1 | 36 | 171 | 4.75 | 2 | 36.00 | 171.00 |
| 9 | Florida State | 3 | 109 | 395 | 3.62 | 4 | 36.33 | 131.67 |
| 10 | Syracuse | 2 | 77 | 485 | 6.30 | 4 | 38.50 | 242.50 |
| 11 | Virginia Tech | 2 | 79 | 530 | 6.71 | 6 | 39.50 | 265.00 |
| 12 | Clemson | 1 | 42 | 147 | 3.50 | 2 | 42.00 | 147.00 |
| 12 | Wake Forest | 1 | 42 | 163 | 3.88 | 2 | 42.00 | 163.00 |
| 14 | Stanford | 3 | 127 | 562 | 4.43 | 8 | 42.33 | 187.33 |