2025 Atlantic Coast Conference Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 09/12/2025
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Vincent Anthony Jr. | Duke | SR | DE | 1 | 3.0 | 17 | 3.00 |
| 2 | Daniel Lyons | FSU | JR | DL | 1 | 1.0 | 15 | 1.00 |
| 3 | Elhadj Fall | Va Tech | JR | DL | 1 | 1.0 | 14 | 1.00 |
| 4 | Will Heldt | Clemson | JR | DE | 1 | 1.0 | 12 | 1.00 |
| 4 | Kendall Johnson | Duke | SO | LB | 1 | 1.0 | 12 | 1.00 |
| 6 | Ahmad Moten, Sr. | Miami (Fl) | JR | DL | 1 | 1.0 | 11 | 1.00 |
| 7 | Akheem Mesidor | Miami (Fl) | SR | DL | 1 | 1.5 | 10 | 1.50 |
| 8 | Stefon Thompson | FSU | SR | LB | 1 | 1.0 | 7 | 1.00 |
| 9 | Deamontae Diggs | FSU | SR | DL | 1 | 1.0 | 6 | 1.00 |
| 9 | Emmett Laws | Va Tech | FR | DL | 1 | 1.0 | 6 | 1.00 |
| 11 | Kemari Copeland | Va Tech | JR | DL | 1 | 0.5 | 5 | 0.50 |
| 11 | Jaden Keller | Va Tech | SR | LB | 1 | 0.5 | 5 | 0.50 |
| 11 | Ben Bell | Va Tech | SR | DL | 1 | 0.5 | 5 | 0.50 |
| 14 | Rueben Bain, Jr. | Miami (Fl) | JR | DL | 1 | 0.5 | 3 | 0.50 |
| 15 | Kelvin Gilliam, Jr. | Va Tech | SR | DL | 1 | 0.5 | 1 | 0.50 |