2025 Big 12 Conference Leaders Rushing Defense - Games Lost Only through 09/18/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Arizona State | 1 | 30 | 66 | 2.20 | 0 | 30.00 | 66.00 |
| 2 | Cincinnati | 1 | 36 | 110 | 3.06 | 0 | 36.00 | 110.00 |
| 3 | West Virginia | 1 | 48 | 182 | 3.79 | 1 | 48.00 | 182.00 |
| 4 | Kansas State | 3 | 161 | 601 | 3.73 | 5 | 53.67 | 200.33 |
| 5 | Kansas | 1 | 47 | 261 | 5.55 | 2 | 47.00 | 261.00 |
| 6 | Colorado | 2 | 100 | 529 | 5.29 | 6 | 50.00 | 264.50 |
| 7 | Baylor | 1 | 52 | 307 | 5.90 | 4 | 52.00 | 307.00 |
| 8 | Oklahoma State | 1 | 37 | 312 | 8.43 | 5 | 37.00 | 312.00 |