2025 Conference USA Leaders Tackles For Loss - Games vs. FBS Power 5 Conference Teams Only through 11/22/2025
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Delaware | 2 | 14.0 | 46 | 7.00 |
| 2 | Sam Houston State | 2 | 11.0 | 35 | 5.50 |
| 3 | Kennesaw State | 2 | 10.0 | 16 | 5.00 |
| 4 | Louisiana Tech | 2 | 9.0 | 38 | 4.50 |
| 4 | Missouri State | 2 | 9.0 | 36 | 4.50 |
| 6 | Middle Tennessee State | 1 | 7.0 | 35 | 7.00 |
| 7 | Western Kentucky | 1 | 6.0 | 22 | 6.00 |
| 8 | Jacksonville State | 1 | 5.0 | 32 | 5.00 |
| 8 | UTEP | 1 | 5.0 | 13 | 5.00 |
| 10 | FIU | 1 | 2.0 | 11 | 2.00 |
| 11 | New Mexico State | 1 | 1.0 | 1 | 1.00 |