2025 Conference USA Leaders Passing Defense - Games vs. FBS Power 5 Conference Teams Only through 12/06/2025
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | UTEP | 1 | 25 | 11 | 44.0 | 114 | 4.6 | 1 | 1 | 87.50 | 25.0 | 114.0 |
| 2 | Louisiana Tech | 2 | 66 | 43 | 65.2 | 383 | 5.8 | 2 | 1 | 120.87 | 33.0 | 191.5 |
| 3 | FIU | 1 | 33 | 19 | 57.6 | 200 | 6.1 | 2 | 0 | 128.49 | 33.0 | 200.0 |
| 4 | Western Kentucky | 1 | 42 | 25 | 59.5 | 202 | 4.8 | 1 | 1 | 103.02 | 42.0 | 202.0 |
| 5 | New Mexico State | 1 | 27 | 19 | 70.4 | 219 | 8.1 | 1 | 2 | 135.91 | 27.0 | 219.0 |
| 6 | Kennesaw State | 2 | 56 | 41 | 73.2 | 498 | 8.9 | 5 | 0 | 177.38 | 28.0 | 249.0 |
| 7 | Middle Tennessee State | 1 | 27 | 23 | 85.2 | 283 | 10.5 | 3 | 1 | 202.49 | 27.0 | 283.0 |
| 8 | Delaware | 2 | 57 | 38 | 66.7 | 582 | 10.2 | 5 | 2 | 174.37 | 28.5 | 291.0 |
| 9 | Jacksonville State | 1 | 33 | 22 | 66.7 | 314 | 9.5 | 2 | 0 | 166.60 | 33.0 | 314.0 |
| 10 | Sam Houston State | 2 | 70 | 52 | 74.3 | 629 | 9.0 | 3 | 2 | 158.20 | 35.0 | 314.5 |
| 11 | Missouri State | 2 | 63 | 48 | 76.2 | 645 | 10.2 | 4 | 1 | 179.97 | 31.5 | 322.5 |