2024 American Athletic Conference Leaders Total Defense - Games vs. FBS Power 5 Conference Teams Only through 01/04/2025
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulsa | 1 | 129 | 431 | 74 | 560 | 7.57 | 560.0 |
| 2 | Navy | 1 | 158 | 275 | 84 | 433 | 5.15 | 433.0 |
| 3 | Florida Atlantic | 1 | 179 | 114 | 61 | 293 | 4.80 | 293.0 |
| 4 | UTSA | 1 | 187 | 427 | 67 | 614 | 9.16 | 614.0 |
| 5 | East Carolina | 1 | 198 | 230 | 61 | 428 | 7.02 | 428.0 |
| 6 | Temple | 1 | 220 | 158 | 65 | 378 | 5.82 | 378.0 |
| 7 | North Texas | 1 | 232 | 354 | 71 | 586 | 8.25 | 586.0 |
| 8 | Rice | 1 | 237 | 142 | 63 | 379 | 6.02 | 379.0 |
| 9 | Memphis | 2 | 243 | 529 | 131 | 772 | 5.89 | 386.0 |
| 10 | UAB | 1 | 266 | 161 | 64 | 427 | 6.67 | 427.0 |
| 11 | South Florida | 2 | 387 | 598 | 131 | 985 | 7.52 | 492.5 |
| 12 | Charlotte | 2 | 491 | 509 | 139 | 1000 | 7.19 | 500.0 |
| 13 | Tulane | 3 | 621 | 653 | 210 | 1274 | 6.07 | 424.7 |