2024 Conference USA Leaders Rushing Defense - Games vs. FBS Power 5 Conference Teams Only through 01/04/2025
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | New Mexico State | 1 | 34 | 209 | 6.15 | 2 | 34.00 | 209.00 |
| 2 | Jacksonville State | 1 | 36 | 233 | 6.47 | 5 | 36.00 | 233.00 |
| 3 | Florida International | 1 | 40 | 234 | 5.85 | 3 | 40.00 | 234.00 |
| 4 | Sam Houston State | 1 | 57 | 384 | 6.74 | 6 | 57.00 | 384.00 |
| 5 | Louisiana Tech | 2 | 76 | 384 | 5.05 | 5 | 38.00 | 192.00 |
| 6 | Middle Tennessee | 2 | 77 | 382 | 4.96 | 9 | 38.50 | 191.00 |
| 7 | Western Kentucky | 2 | 82 | 445 | 5.43 | 8 | 41.00 | 222.50 |
| 8 | UTEP | 2 | 86 | 464 | 5.40 | 7 | 43.00 | 232.00 |