2022 American Athletic Conference Leaders Total Offense - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | UCF | 3 | 620 | 378 | 216 | 998 | 4.62 | 332.7 |
| 2 | SMU | 2 | 255 | 741 | 182 | 996 | 5.47 | 498.0 |
| 3 | Cincinnati | 3 | 208 | 762 | 197 | 970 | 4.92 | 323.3 |
| 4 | Tulane | 2 | 465 | 410 | 118 | 875 | 7.42 | 437.5 |
| 5 | Houston | 2 | 261 | 538 | 138 | 799 | 5.79 | 399.5 |
| 6 | South Florida | 2 | 334 | 226 | 137 | 560 | 4.09 | 280.0 |
| 7 | Tulsa | 1 | 262 | 195 | 77 | 457 | 5.94 | 457.0 |
| 8 | Temple | 2 | 114 | 329 | 120 | 443 | 3.69 | 221.5 |
| 9 | East Carolina | 1 | 116 | 267 | 68 | 383 | 5.63 | 383.0 |
| 10 | Memphis | 1 | 129 | 165 | 51 | 294 | 5.76 | 294.0 |