2022 American Athletic Conference Leaders Total Offense - Games vs. Ranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Tulane | 2 | 465 | 410 | 118 | 875 | 7.42 | 437.5 |
| 2 | South Florida | 1 | 118 | 259 | 51 | 377 | 7.39 | 377.0 |
| 3 | Navy | 1 | 255 | 108 | 59 | 363 | 6.15 | 363.0 |
| 4 | Memphis | 2 | 232 | 477 | 125 | 709 | 5.67 | 354.5 |
| 5 | East Carolina | 1 | 131 | 288 | 75 | 419 | 5.59 | 419.0 |
| 6 | SMU | 2 | 245 | 701 | 182 | 946 | 5.20 | 473.0 |
| 7 | UCF | 2 | 481 | 397 | 180 | 878 | 4.88 | 439.0 |
| 7 | Cincinnati | 1 | 235 | 102 | 69 | 337 | 4.88 | 337.0 |
| 9 | Houston | 1 | 175 | 208 | 81 | 383 | 4.73 | 383.0 |
| 10 | Tulsa | 1 | 111 | 146 | 59 | 257 | 4.36 | 257.0 |