2020 American Athletic Conference Leaders Total Offense - Games vs. Ranked Teams Only (AP Poll) through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 2 | 250 | 475 | 131 | 725 | 5.53 | 362.5 |
| 2 | Houston | 2 | 221 | 499 | 139 | 720 | 5.18 | 360.0 |
| 3 | East Carolina | 2 | 332 | 417 | 149 | 749 | 5.03 | 374.5 |
| 4 | Memphis | 1 | 5 | 316 | 64 | 321 | 5.02 | 321.0 |
| 5 | Tulsa | 1 | 166 | 166 | 67 | 332 | 4.96 | 332.0 |
| 6 | UCF | 3 | 435 | 790 | 257 | 1225 | 4.77 | 408.3 |
| 7 | Tulane | 1 | 226 | 76 | 68 | 302 | 4.44 | 302.0 |
| 8 | South Florida | 3 | 311 | 516 | 206 | 827 | 4.01 | 275.7 |
| 9 | SMU | 2 | 226 | 415 | 161 | 641 | 3.98 | 320.5 |
| 10 | Navy | 2 | 245 | 57 | 111 | 302 | 2.72 | 151.0 |