2022 American Athletic Conference Leaders Passes Defended - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|
| 1 | Tulane | 10 | 8 | 40 | 48 | 4.80 |
| 1 | East Carolina | 8 | 8 | 18 | 26 | 3.25 |
| 3 | SMU | 8 | 5 | 18 | 23 | 2.88 |
| 4 | UCF | 8 | 4 | 33 | 37 | 4.63 |
| 4 | Houston | 6 | 4 | 24 | 28 | 4.67 |
| 6 | Tulsa | 7 | 3 | 24 | 27 | 3.86 |
| 6 | South Florida | 8 | 3 | 21 | 24 | 3.00 |
| 6 | Cincinnati | 6 | 3 | 17 | 20 | 3.33 |
| 6 | Memphis | 6 | 3 | 15 | 18 | 3.00 |
| 6 | Navy | 8 | 3 | 13 | 16 | 2.00 |
| 11 | Temple | 6 | 1 | 24 | 25 | 4.17 |