2022 American Athletic Conference Leaders Rushing Defense - Games in August/September Only through 01/09/2023
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Navy | 3 | 89 | 207 | 2.33 | 2 | 29.67 | 69.00 |
| 2 | East Carolina | 4 | 145 | 442 | 3.05 | 2 | 36.25 | 110.50 |
| 3 | Cincinnati | 4 | 180 | 501 | 2.78 | 3 | 45.00 | 125.25 |
| 4 | Memphis | 4 | 154 | 509 | 3.31 | 6 | 38.50 | 127.25 |
| 5 | Temple | 4 | 161 | 520 | 3.23 | 1 | 40.25 | 130.00 |
| 6 | UCF | 4 | 139 | 577 | 4.15 | 3 | 34.75 | 144.25 |
| 7 | Houston | 5 | 168 | 676 | 4.02 | 8 | 33.60 | 135.20 |
| 8 | Tulane | 5 | 207 | 680 | 3.29 | 2 | 41.40 | 136.00 |
| 9 | SMU | 4 | 163 | 722 | 4.43 | 7 | 40.75 | 180.50 |
| 10 | Tulsa | 4 | 175 | 785 | 4.49 | 7 | 43.75 | 196.25 |
| 11 | South Florida | 4 | 153 | 982 | 6.42 | 13 | 38.25 | 245.50 |