2022 American Athletic Conference Leaders Passing Defense - Games vs. Unranked Teams Only (AP Poll) through 01/09/2023
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 12 | 370 | 202 | 54.6 | 2207 | 6.0 | 14 | 11 | 111.25 | 30.8 | 183.9 |
| 2 | SMU | 11 | 355 | 195 | 54.9 | 2524 | 7.1 | 19 | 10 | 126.68 | 32.3 | 229.5 |
| 3 | Tulane | 12 | 380 | 219 | 57.6 | 2301 | 6.1 | 17 | 11 | 117.46 | 31.7 | 191.8 |
| 4 | Tulsa | 11 | 319 | 184 | 57.7 | 2351 | 7.4 | 19 | 5 | 136.11 | 29.0 | 213.7 |
| 5 | UCF | 12 | 382 | 225 | 58.9 | 2482 | 6.5 | 8 | 5 | 117.76 | 31.8 | 206.8 |
| 6 | Memphis | 11 | 371 | 224 | 60.4 | 2529 | 6.8 | 18 | 15 | 125.56 | 33.7 | 229.9 |
| 7 | Navy | 11 | 327 | 203 | 62.1 | 2733 | 8.4 | 21 | 7 | 149.20 | 29.7 | 248.5 |
| 8 | Houston | 12 | 453 | 288 | 63.6 | 3433 | 7.6 | 29 | 8 | 144.84 | 37.8 | 286.1 |
| 9 | Temple | 12 | 326 | 209 | 64.1 | 2383 | 7.3 | 21 | 6 | 143.09 | 27.2 | 198.6 |
| 10 | East Carolina | 12 | 402 | 261 | 64.9 | 3456 | 8.6 | 25 | 11 | 152.19 | 33.5 | 288.0 |
| 11 | South Florida | 11 | 339 | 252 | 74.3 | 3055 | 9.0 | 23 | 6 | 168.89 | 30.8 | 277.7 |