2022 American Athletic Conference Leaders Interceptions - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jireh Wilson | ECU | JR | SAF | 1 | 1 | 34 | 0 | 1.00 |
| 1 | Quindell Johnson | Memphis | SR | DB | 1 | 1 | 0 | 0 | 1.00 |
| 3 | Jayce Rogers | Houston | SR | DB | 2 | 1 | 54 | 1 | 0.50 |
| 3 | Art Green | Houston | SR | DB | 2 | 1 | 37 | 0 | 0.50 |
| 3 | Dwayne Boyles | S Florida | SR | LB | 2 | 1 | 37 | 0 | 0.50 |
| 3 | Gervarrius Owens | Houston | SR | DB | 2 | 1 | 24 | 0 | 0.50 |
| 3 | Aamaris Brown | S Florida | FR | DB | 2 | 1 | 0 | 0 | 0.50 |
| 3 | Jarius Monroe | Tulane | JR | DB | 2 | 1 | 0 | 0 | 0.50 |
| 9 | Bryon Threats | Cincinnati | SO | S | 3 | 1 | 28 | 0 | 0.33 |
| 9 | Armorion Smith | Cincinnati | FR | S | 3 | 1 | 20 | 0 | 0.33 |
| 9 | Ja'Von Hicks | Cincinnati | SR | S | 3 | 1 | 19 | 0 | 0.33 |
| 9 | Taj Ward | Cincinnati | SR | CB | 3 | 1 | 4 | 0 | 0.33 |
Note: To qualify, player must have played in 75% of his team's games.