2022 American Athletic Conference Leaders Interceptions - Games Lost Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Jireh Wilson | ECU | JR | SAF | 5 | 2 | 34 | 0 | 0.40 |
| 1 | Quindell Johnson | Memphis | SR | DB | 5 | 2 | 4 | 0 | 0.40 |
| 3 | Art Green | Houston | SR | DB | 4 | 1 | 37 | 0 | 0.25 |
| 3 | Gervarrius Owens | Houston | SR | DB | 4 | 1 | 24 | 0 | 0.25 |
| 3 | Davonte Brown | UCF | JR | CB | 4 | 1 | 22 | 0 | 0.25 |
| 3 | Armorion Smith | Cincinnati | FR | S | 4 | 1 | 20 | 0 | 0.25 |
| 3 | Ja'Von Hicks | Cincinnati | SR | S | 4 | 1 | 19 | 0 | 0.25 |
| 8 | Aamaris Brown | S Florida | FR | DB | 10 | 2 | 0 | 0 | 0.20 |
| 8 | Jayce Rogers | Houston | SR | DB | 5 | 1 | 54 | 1 | 0.20 |
| 8 | Juan Powell | ECU | SO | CB | 5 | 1 | 2 | 0 | 0.20 |
| 11 | Shanon Reid | SMU | SR | LB | 6 | 1 | 6 | 0 | 0.17 |
| 11 | Davion Ross | Memphis | JR | DB | 6 | 1 | 0 | 0 | 0.17 |
| 13 | Kendarin Ray | Tulsa | SR | S | 7 | 1 | 23 | 0 | 0.14 |
| 14 | John Marshall | Navy | SR | STR | 8 | 1 | 0 | 0 | 0.13 |
| 15 | Layton Jordan | Temple | JR | OLB | 9 | 1 | 35 | 1 | 0.11 |
| 15 | Muheem McCargo | Temple | SO | SAF | 9 | 1 | 35 | 0 | 0.11 |
| 15 | Jalen McMurray | Temple | FR | CB | 9 | 1 | 4 | 0 | 0.11 |
| 18 | Mekhi LaPointe | S Florida | SR | DB | 10 | 1 | 12 | 0 | 0.10 |
| 18 | Matthew Hill | S Florida | JR | S | 10 | 1 | 0 | 0 | 0.10 |
| 20 | Dwayne Boyles | S Florida | SR | LB | 11 | 1 | 37 | 0 | 0.09 |
Note: To qualify, player must have played in 75% of his team's games.